Archives

Here the results of the national multicenter study on the quality of life of COVID-19 patients one year after ICU discharge: around 20% of the enrolled patients were from Pavia!   Full text here on the Journal of Clinical Medicine   Abstract Background: Investigating the health-related quality of life (HRQoL) after intensive care unit (ICU) discharge […]

Collecting the results of international fellows coming to Pavia from Eindhoven Technical University for research on respiratory patients: machine learning for detection and classification of patient-ventilator asynchronies. Free full text here on Computer Methods and Programs in Biomedicine Abstract Background and objective Mechanical ventilation is a lifesaving treatment for critically ill patients in an Intensive Care […]

Can we use nasal swab to guide empiric antibiotic therapy in ventilator-associated pneumonia? See the results from the retrospective analysis of more than 1400 patients in our ICU. Free full text here on Antibiotics Abstract The guidelines on ventilator-associated pneumonia (VAP) recommend an empiric therapy against methicillin-resistant Staphylococcus aureus (MRSA) according to its prevalence rate. […]

Enrolments are open! See rationale and details of the IPERPEEP protocol Free full text here on Trial   Background In acute respiratory distress syndrome (ARDS), response to positive end-expiratory pressure (PEEP) is variable according to different degrees of lung recruitability. The search for a tool to individualize PEEP based on patients’ individual response is warranted. […]

COVID-19 vaccine significantly reduced the risk of ICU admission for COVID-19 pneumonia, even when adjusted by confounders as age and sex. No difference in ICU outcome was observed between vaccinated and unvaccinated patients, even if vaccinated ones had more risk factors since they were older and with more comorbidities. Have a look the the results of […]

Can we improve patient-ventilator interaction with waveform analysis? Have a look to this prospective randomised crossover study on Anaesthesia Critical Care & Pain Medicine.   Abstract Objective To test the performance of a software able to control mechanical ventilator cycling-off by means of automatic, real-time analysis of ventilator waveforms during pressure support ventilation. Design Prospective […]

How to use cardiac, diaphragm and lung ultrasound to improve the assessment of the patients to wean from mechanical ventilation? Here a narrative review on Current Opinion in Critical Care Available on Pubmed   Abstract Purpose of review: Due to heart, lung and diaphragm interactions during weaning from mechanical ventilation, an ultrasound integrated approach may be useful […]