• Innovation
    Promotion of technological and clinical innovation in critical care
  • Grip
    In-vitro and in-vivo research adherent to clinical practice and relevant for ICU every-day activities
  • Sharing
    International spread of ideas, innovation and research

Our philosophy

The GRIP (Group for Research in Intensive care in Pavia) is founded in 2015 by a group of intensivists working at Intensive Care Units of Policlinico S. Matteo in Pavia. We are a group of young doctors and researchers who dedicated in the last years great energy, enthusiasm and time to develop new ideas, improve technology and optimize quality of care for critical patients. Our group is characterized by strong international connections for both clinical research and technological developement. Our missions are:


  1. 1

    Intensive care units are highly technological; therefore, development of innovative instruments and optimization of existing ones can have a deep clinical impact. We have strong national and international collaborations with research and development sections of industries involved in the field and with many universities in order to push technology forward.

  2. 2

    Our aim is to promote and support a research projects gripping the real world. First, this means we support research with high clinical impact and strong everyday applicability. Second, we support researchers, offering work possibilities for young professionals.

  3. 3

    We aim to share our ideas, projects and results with scientific community; we have strong national and international research cooperation and  researcher exchange programs with multiple university centers.

Setting positive end-expiratory pressure: using the pressure-volume curve

Have a look to this brand new review to improve your use of pressure-volume curves to set PEEP in ICU patients - on Current Opinion in Critical Care

Setting positive end-expiratory pressure: using the pressure-volume curve

Francesco Mojoli 1 2Marco Pozzi 2Eric Arisi 2


Purpose of review: To discuss the role of pressure-volume curve (PV curve) in exploring elastic properties of the respiratory system and setting mechanical ventilator to reduce ventilator-induced lung injury. Recent findings: Nowadays, quasi-static PV curves and loops can be easily obtained and analyzed at the bedside without disconnection of the patient from the ventilator. It is shown that this tool can provide useful information to optimize ventilator setting. For example, PV curves can assess for patient's individual potential for lung recruitability and also evaluate the risk for lung injury of the ongoing mechanical ventilation setting. Summary: In conclusion, PV curve is an easily available bedside tool: its correct interpretation can be extremely valuable to enlighten potential for lung recruitability and select a high or low positive end-expiratory pressure (PEEP) strategy. Furthermore, recent studies have shown that PV curve can play a significant role in PEEP and driving pressure fine tuning: clinical studies are needed to prove whether this technique will improve outcome.
No Events were found.