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Abstract The aim of this study was to measure the serum levels of catecholamines in patients admitted to intensive care unit (ICU) with COVID-19-related acute respiratory distress syndrome (ARDS) and describe their relation with clinical, inflammatory and echocardiographic parameters. Serum levels of endogenous catecholamines (norepinephrine, epinephrine and dopamine) were measured at ICU admission. We enrolled […]

Abstract Candida-related bloodstream infections (BSIs) represent a severe condition associated with health care in the critical patient, with an increasing incidence of Candida non-albicans species. These infections could lead to several and unusual complications in high-risk patients due to various factors, including a prolonged hospital stay and invasive medical interventions. Here we report a case […]

Have a look to this review on Mechanical Circulatory support in ventricular arrhythmias on Frontiers in Cardiovascular Medicine   Free full text here Abstract In atrial and ventricular tachyarrhythmias, reduced time for ventricular filling and loss of atrial contribution lead to a significant reduction in cardiac output, resulting in cardiogenic shock. This may also occur […]

In this retrospective case-control study, barotrauma was recorded in 1.00% of patients, affecting mainly patients with more severe COVID-19 disease. It was independently associated with mortality.   Free full text here on Pulmonology   Abstract Background The risk of barotrauma associated with different types of ventilatory support is unclear in COVID-19 patients. The primary aim of […]

Abstract This multicenter observational study included 171 COVID-19 adult patients hospitalized in the ICUs of nine hospitals in Lombardy (Northern Italy) from December, 1st 2021, to February, 9th 2022. During the study period, the Delta/Omicron variant ratio of cases decreased with a delay of two weeks in ICU patients compared to that in the community; […]

Free full text here on the Journal of Clinical Medicine   Abstract Background: Acute kidney injury (AKI) is common in critically ill patients admitted to intensive care units (ICU) and is frequently associated with poorer outcomes. Hence, if an indicator is available for predicting severe AKI within the first few hours of admission, management strategies […]

An insight from the Lung Safe study focused on mechanical ventilation in cardiogenic edema: higher airway pressure seems to be associated with mortality.   Free full text here on the Journal of Intensive Care Abstract Background Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further […]

Here the results of the national multicenter study on the quality of life of COVID-19 patients one year after ICU discharge: around 20% of the enrolled patients were from Pavia!   Full text here on the Journal of Clinical Medicine   Abstract Background: Investigating the health-related quality of life (HRQoL) after intensive care unit (ICU) discharge […]

Collecting the results of international fellows coming to Pavia from Eindhoven Technical University for research on respiratory patients: machine learning for detection and classification of patient-ventilator asynchronies. Free full text here on Computer Methods and Programs in Biomedicine Abstract Background and objective Mechanical ventilation is a lifesaving treatment for critically ill patients in an Intensive Care […]